Babesia canis invades red blood cells causing lethargy weakness, anorexia, fever, pale mucous membranes,and dark discoloration of the urine.
Babesia gibsoni invades red blood cells causing dark urine, fever, weakness, pale mucous membranes, depression, an enlarged spleen, and thrombocytepenia.
Anaplasmaplatys infects platelets causing thrombocytopenia. Infected dogs may develop bruising or bleeding (including nosebleeds), especially during the early stages of infection when platelet counts may be at their lowest.