Case study: Feline infectious peritonitis in a cat presented because of papular skin lesions
Robert Lo, Ph.D, D.V.M
A 19-week-old neutered male domestic shorthair cat presented only multiple raised pruritic skin lesions along the dorsal head and back and no other symptoms. The cat showed poor appetite and spreading of the skin lesions five days after initial treatment, and then biopsies were taken and submitted to the dermatopathology service. Histopathology indicated strong suspicion of FIP. With cat’s health getting worse, euthanasia was performed. Then, necropsy was also performed. Abundant viscous serofibrinous effusions were found in the abdomen, thorax, and pericardium. Multiple white nodules were observed in the lungs, liver, and kidney. Histologic examination revealed multifocal to coalescing areas of pyogranulomatous inflammation in the affected tissues. Dermal necrosis was observed in skin sections. Immunohistochemical staining for intracellular feline coronavirus showed positive staining within the cytoplasm of macrophages in the lung, kidney, skin, and brain. Feline infectious peritonitis with associated cutaneous lesions was diagnosed in this cat based on gross and histologic lesions along with immunohistochemistry results.
Figure 1: A — Skin lesions (multiple round raised skin nodules) on the dorsal surface of the head and neck. B —Dermal necrosis was observed in histological sections of skin; H&E. C —Immunohistochemical staining for intracellular feline coronavirus showed positive brown staining in skin section. (Redford T, Al-Dissi AN. Feline infectious peritonitis in a cat presented because of papular skin lesions., Can Vet J. 2019 Feb;60(2):183-185.)
Original paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340254/