Neoplasia: The Danger of Feline Leukemia Virus
Feline Leukemia Virus (FeLV) remains one of the most consequential retroviruses affecting domestic cats, not only due to its immunosuppressive effects but also its strong association with neoplastic diseases. Among FeLV-positive cats, neoplasia—particularly lymphoma—is a leading cause of mortality. 1. How does FeLV Causes Cancer? FeLV integrates its RNA into the host’s DNA, altering cellular control mechanisms. This can activate oncogenes or disrupt tumor suppressor genes, leading to unchecked cell proliferation. Unlike other viruses, FeLV has a unique ability to directly induce tumor formation, particularly in hematopoietic and lymphoid tissues. 2. Common Types of FeLV-Associated Tumors Lymphoma: The most common neoplasm in FeLV-positive cats, particularly mediastinal, multicentric, and spinal forms. Leukemia: Especially acute lymphoblastic leukemia (ALL), often aggressive and rapidly progressive. Other Neoplasms: Less commonly, FeLV is associated with fibrosarcomas, myeloproliferative disorders, and osteochondromas. 3. Patient Profile and Risk Factors Age: FeLV-related tumors tend to develop in younger cats, often under 5 years of age. Transmission: FeLV spreads through saliva, nasal secretions, and close contact—making multi-cat environments particularly risky. Co-factors: Immunosuppression, co-infections (e.g., FIV), and genetic predisposition may worsen outcomes. 4. Clinical Signs: Generalized lymphadenopathy Dyspnea (especially with mediastinal involvement) Pale mucous membranes, anemia Weight loss, lethargy Neurologic deficits (with spinal lymphoma) GI signs (vomiting, diarrhea, melena) 5. Diagnostic tests: FeLV Testing: Rapid Test, ELISA and PCR testing to confirm infection status. Imaging: Thoracic radiographs, ultrasound, or CT scans for mass detection. Cytology/Histopathology: Fine needle aspirates or biopsies to confirm neoplastic origin. 6. Prevention: Vaccination: FeLV vaccines are effective at reducing infection rates, especially in high-risk populations. Routine Testing: Especially important for kittens, newly adopted cats, and multi-cat households. Environmental Control: Keeping FeLV-positive cats indoors and separated from uninfected cats. FeLV is not only an infectious threat but a potent oncogenic driver. Understanding its role in feline neoplasia underscores the importance of screening, prevention, and early intervention.
Urinary Tract Infections (UTIs) in Dogs: Why my…?
Urinary tract infections (UTIs) are common in dogs and can affect their comfort, health, and behavior. In this article, we will address the common questions that dog owners have regarding their dog urination. Early detection and treatment are essential to prevent complications such as kidney infections or bladder stones. 🔍 What is a UTI in Dogs? A urinary tract infection is typically caused by bacteria (most commonly Escherichia coli) from the rectum, skin, or hair near the entering the urethra and multiplying into the bladder. Less commonly, fungi, virus or other pathogens may be involved. UTIs can affect the lower urinary tract (bladder and urethra) or upper urinary tract (ureters and kidneys). Lower UTIs are more common and less severe, while upper UTIs is very dangerous and can be life-threatening. 🧬 Causes Bacterial contamination (e.g., from feces or environment) Poor hygiene, especially in long-haired or incontinent dogs Urinary retention (not urinating frequently) Underlying health problems: Diabetes mellitus Cushing’s disease Kidney disease Bladder stones or tumors Weakened immune system Congenital abnormalities of the urinary tract 🚨 Clinical Signs Some dogs show clear symptoms, while others may be asymptomatic, especially early on. Pet owners should watch for: Frequent urination (pollakiuria) Straining or pain while urinating Small amount or no urine (dysuria) Blood in urine (hematuria) Cloudy color or foul-smelling urine Accidents in the house (even if previously house-trained) Licking the genital area excessively Fever or lethargy (in severe or kidney-involved infections) Loss of appetite 🩺 Diagnosis A veterinarian will typically perform: Urinalysis – to check for bacteria, white blood cells, pH, crystals Urine culture and sensitivity test – to identify the exact bacteria and the most effective antibiotic Blood tests – to assess kidney function or underlying illness Imaging (X-ray or ultrasound) – if stones, tumors, or structural abnormalities are suspected 💊 Treatment Antibiotics – prescribed based on culture results Pain relief / anti-inflammatories Increased water intake – to flush the urinary system Dietary changes – especially if crystals or stones are present Surgery – in cases of tumors, large stones, or anatomical issues 🔄 Recurring UTIs Recurrent infections may signal underlying problems. Your vet might recommend: Advanced imaging Endoscopy Long-term antibiotic therapy Immune function testing 🛡️ Prevention Tips Ensure clean drinking water at all times (Flowing water is preferred) Encourage regular potty breaks Maintain proper hygiene, especially in long-haired breeds Regular vet checkups, especially for senior dogs Control underlying conditions like diabetes or bladder stones
Unmasking the Spread: How Antibiotic Resistance Travels and Grows
Antibiotic resistance is no longer just a human healthcare issue—it’s a shared threat across both medical and veterinary fields. As veterinarians, we stand at the front lines, where responsible antibiotic use can make a critical difference. But how exactly does antibiotic resistance develop and spread? Let’s break it down. Step 1: Antibiotic Use in Animals The journey begins on farms, where animals such as chickens, pigs, and cows are routinely given antibiotics. It could be from medicated feed, or disease therapy, and while this may help prevent disease and promote growth, it also creates a dangerous side effect—bacteria in the animals’ systems can become resistant to antibiotics. These drug-resistant bacteria are then carried in the animals’ bodies and waste. Step 2: Contamination Through Food and Water Animal waste, rich in resistant bacteria, is often used as fertilizer or finds its way into water sources. Crops grown in this environment may become contaminated. These bacteria can remain on or in the crops, making their way into the human digestive system when consumed. Step 3: Spread Through Meat Consumption Drug-resistant bacteria also linger on raw meat. If not properly handled or cooked, these bacteria can transfer to humans, adding another entry point for resistance to spread in the population. Step 4: Resistance in the Community Once in the human body, drug-resistant bacteria can settle and multiply. For example, someone like “John” may take antibiotics and unknowingly harbor resistant bacteria in his system. He then interacts with others in his household or community, unknowingly spreading the bacteria. Step 5: Amplification in Healthcare Settings The situation worsens if John seeks care in a hospital or nursing home. These environments often house vulnerable individuals and use intensive antibiotic treatments. Here, resistant bacteria can be spread directly from patient to patient or indirectly via the unclean hands of healthcare workers and contaminated surfaces. These healthcare facilities, intended to heal, can become hotspots for the spread of resistant germs. Step 6: Cycle Repeats When patients return home, they may continue to carry and transmit resistant bacteria, perpetuating the cycle. As these bacteria travel from animals to food, to people, to hospitals, and back into the community, antibiotic resistance continues to grow and evolve. Veterinary Responsibility To slow the spread: Use antibiotics only when necessary and with proper diagnostics. Follow strict hygiene protocols in clinics and farms. Educate clients on proper treatment adherence and the risks of misuse. Support preventive care, like vaccinations and good nutrition, to reduce infection risks. By staying informed and vigilant, veterinarians play a crucial role in preserving antibiotic effectiveness—for both animals and people.
Von Willebrand’s Disease (vWD) in Dogs
Von Willebrand Disease (vWD) is the most common inherited bleeding disorder in dogs. It’s caused by a deficiency or dysfunction of a specific blood clotting protein called von Willebrand factor (vWF). This protein helps blood platelets stick together to seal broken blood vessels and stop bleeding. Without enough functional vWF, dogs with vWD can experience excessive or prolonged bleeding. There are three types of von Willebrand disease: Type 1: There are low amounts of vWF proteins with normal structure. Type 2: Some vWF proteins are present,but there is an abnormal structure of the proteins which doesn’t function normally. Type 3: There are little to no vWF proteins available; this is the most severe form. Signs and Symptoms Symptoms of vWD can vary from mild to severe. Common signs include: Nosebleeds Bleeding gums Prolonged bleeding after surgery or injury Blood in urine or stool Bruising easily Diagnosis and Treatment A veterinarian can diagnose vWD through blood tests such as basic blood cell count, chemistry, and coagulation profile that measure vWF levels and clotting ability. DNA testing is also available to identify carriers, especially in breeds prone to the disease. There’s no cure for vWD, but mild cases often require no treatment. In more serious cases, veterinarians may use medications like Desmopressin acetate (DDAVP) or blood transfusions to manage bleeding episodes. It’s important to avoid medications like aspirin, heparin or sulfa-type antibiotics that can worsen bleeding. Prevention Responsible breeding practices are key to reducing the spread of vWD. Breeders should screen their dogs for the disease and avoid breeding affected animals.
Qmini Real-Time PCR Series Maintenance Video
Overseas Sales Representative
Overseas Sales Representative Apply now Canada Full-time Requires business travel (total duration per year TBD) Hiring 1–2 positions. Overseas Sales, Overseas Sales Manager, Marketing Planner Read more Job description Demonstrates expert knowledge of IVDs product, customer base (animal clinics and vets), business strategy and competitive environment; stays abreast of key market access issues/trends important for educating customers. Uphold high ethical and performance standards in all business interactions to preserve bioguard’s outstanding reputation in the animal disease community. Collaborating with cross-functional teams – from production to product marketing and legal – to produce effective communications. Obtaining necessary consent and providing final approval on all marketing communications. This role is to be filled within Latin America. Requirements Able to communicate in English or Chinese. Bachelor’s degree in veterinary medicine, medical laboratory science and biotechnology, biotechnology, biochemistry, or related field preferred. Institutional sales experience preferred. Possess strong interpersonal skills to establish rapport swiftly and maintain relationships effectively. Demonstrated motivation, goal orientation, and exceptional organizational abilities, particularly in multitasking environments. Job description Demonstrates expert knowledge of IVDs product, customer base (animal clinics and vets), business strategy and competitive environment; stays abreast of key market access issues/trends important for educating customers. Uphold high ethical and performance standards in all business interactions to preserve bioguard’s outstanding reputation in the animal disease community. Collaborating with cross-functional teams – from production to product marketing and legal – to produce effective communications. Obtaining necessary consent and providing final approval on all marketing communications. This role is to be filled within Latin America. Requirements Able to communicate in English or Chinese. Bachelor’s degree in veterinary medicine, medical laboratory science and biotechnology, biotechnology, biochemistry, or related field preferred. Institutional sales experience preferred. Possess strong interpersonal skills to establish rapport swiftly and maintain relationships effectively. Demonstrated motivation, goal orientation, and exceptional organizational abilities, particularly in multitasking environments.
Qmini Real-Time PCR Series -Avian Pathogen Nucleic Acid Extraction Kit Instruction Video
Why Are Cats More Prone to CKD (Chronic Kidney Disease)?
Chronic kidney disease (CKD) can affect cats at any age but is more commonly diagnosed in middle-aged and senior cats, typically those over seven years old. There are several reasons that causes CKD, which are: 1. Natural Aging Process: Unlike dogs, whose kidneys tend to fail due to infections or inherited conditions, CKD in cats is often linked to gradual wear and tear on the kidneys as they age. 2. Low Thirst Drive: Cats evolved from desert animals and naturally have a low thirst drive. This means they don’t drink as much water as they should, putting extra strain on their kidneys. 3. Protein Metabolism: Cats require a high-protein diet, but their kidneys have to filter out protein waste. Over time, this can contribute to kidney damage. 4. Genetic Factors: Some breeds, like Persians, Siamese, and Abyssinians, are more genetically predisposed to kidney disease. 5. Silent Progression: CKD in cats often goes unnoticed because symptoms—like weight loss, increased thirst, and urination—develop slowly. By the time a cat is diagnosed, the disease is usually in an advanced stage.
Bioguard x 92nd PVMA : Advancing Veterinary Diagnostics
The 92nd PVMA Scientific Conference and Annual Convention has been an incredible experience filled with “learning, innovation, and collaboration”. As we wrap up Day 1 & 2, Bioguard is proud to have played a part in this event in philippine, bringing comprehensive veterinary diagnostic solutions to phillippine veterinary field. Showcasing Bioguard Veterinary Diagnostics Products At 92nd PVMA, Bioguard introduced two of our advanced diagnostic equipment: Qmini Real-Time PCR Analyzer – A rapid and precise in-clinic PCR test that enhances veterinary disease detection. miniCHEM Biochemical & Coagulation Analyzer –A bifunction biochemistry analyzer to deliver #reliable #results, and all it needs is #MicroVolume of #blood sample for each #test. Veterinarians and industry professionals had the opportunity to explore our comprehensive solutions and discussions about their potential impact on the veterinary healthcare field. We appreciate the overwhelming interest expressed by attendees. Engaging with Veterinary Experts Beyond showcasing our products, PVMA 2025 allowed us to connect with leading professionals in the veterinary field. Among them were: Dr. Joel Tolentino – A professional veterinarian, also our speaker for bioguard online webinars, Canine Vector Borne Diseases- Diagnosis in the Companion Animal Practice Dr. Paul – The first veterinarian in the Philippines to install the Qmini Real-Time PCR Analyzer. Dr. Paul is going to lead a workshop with Maveson next month, further educating veterinarians on advanced diagnostic techniques. These interactions reinforce our commitment to supporting veterinarians with the latest diagnostic advancements, ensuring better pet healthcare. Future Commitment to Veterinary Experts Bioguard remains dedicated to delivering high-quality, innovative veterinary diagnostic solutions that empower veterinarians worldwide. We extend our heartfelt gratitude to all who visited our booth, engaged in discussions, and contributed to the success of PVMA 2025. For further information about our diagnostic solutions, feel free to contact us: 📩 Email: service@bioguard.com.tw PVMA webisite: https://www.facebook.com/profile.php?id=100064780414291 We look forward to seeing you again at future veterinary conferences!
On-Site Technical Support
On-Site Technical Support Apply now Europe Full-time Requires business travel (total duration per year TBD) Hiring 1–2 positions. Business support, Product after-sales technical services Read more Job description Resolve Issues Related To The Product. Managing And Processing Customer Orders. Prepare Accurate And Timely Reports. Researching Technical Issues. Configure Operating Systems. Monitor And Maintain Bioguard Products. Provide On-site Support. Responding To Client Vet Support Requests. Tracking And Managing Work Records. Monitoring Protocols And Ensure Adherence. Providing Basic Product Training Requirements Proficient in English. Bachelor’s degree in veterinary medicine, medical laboratory science and biotechnology, biotechnology, biochemistry, or related field required. Institutional sales experience preferred. Strong interpersonal skills with ability to establish rapport quickly, build and maintain relationships. Highly motivated, goal oriented with strong organizational skills, especially in a multi-tasking environment. Ability to work both independently and as part of a team. Computer proficiency (Microsoft Windows, Excel, Word and Outlook). Job description Resolve Issues Related To The Product. Managing And Processing Customer Orders. Prepare Accurate And Timely Reports. Researching Technical Issues. Configure Operating Systems. Monitor And Maintain Bioguard Products. Provide On-site Support. Responding To Client Vet Support Requests. Tracking And Managing Work Records. Monitoring Protocols And Ensure Adherence. Providing Basic Product Training Requirements Proficient in English. Bachelor’s degree in veterinary medicine, medical laboratory science and biotechnology, biotechnology, biochemistry, or related field required. Institutional sales experience preferred. Strong interpersonal skills with ability to establish rapport quickly, build and maintain relationships. Highly motivated, goal oriented with strong organizational skills, especially in a multi-tasking environment. Ability to work both independently and as part of a team. Computer proficiency (Microsoft Windows, Excel, Word and Outlook).