Breed-related disease: Affenpinscher
John K. Rosembert The Affenpinscher also known as the “monkey dogs,” could be described as cheeky little monkeys. That isn’t to say that they’re naughty but a comical little dog with bags of personality. He is a small, compact terrier-type dog with bushy eyebrows and a mischievous monkey-like expression. The coat is rough and of uneven length over the body adding to their somewhat comical appearance. They have a lively, strutting movement. He is one of the oldest breeds, known to have been in existence in the 17th century and similar dogs appear in paintings of the fifteenth and sixteenth centuries. The Affenpinscher adores his family and is fine with other family pets, especially when raised with them. In the home, he is an inquisitive busybody who must check out new sights and sounds. His playful antics are delightfully entertaining as he bats toys around with his agile paws. Affenpinschers do have a mind of their own, and without a firm hand can be obstinate and demanding, tossing tantrums or sulking when they don’t get their own way. It might make you laugh, but spoiling is not recommended for this breed, especially since he is so bright and does respond well to calm, patient training, like most terrier-type dogs, the Affenpinscher is proud and sensitive and does not take kindly to being teased. This breed is happiest in a home without young children. According to dog experts, Affenpinscher Dogs score 3 out of 5 in the scale of breeds that are considered the most healthy dog breeds. They are generally healthy, but like all breeds, they’re prone to certain health conditions. Not all Affens will get any or all of these diseases, but it’s important to be aware of them if you’re considering this breed. Patellar Luxation: Also known as “slipped stifles,” this is a common problem in small dogs. It is caused when the patella, which has three parts-the femur (thigh bone), patella (knee cap), and tibia (calf)–is not properly lined up. This causes lameness in the leg or an abnormal gait, sort of like a skip or a hop. Legg-Perthes Disease: Generally a disease of small breeds, this condition–a deformity of the ball of the hip joint–usually appears at 6 to 9 months of age and can be confused with hip dysplasia. It causes wearing and arthritis. It can be repaired surgically, and the prognosis is good with the help of rehabilitation therapy afterward. Hip Dysplasia: This is a heritable condition in which the thighbone doesn’t fit snugly into the hip joint. Some dogs show pain and lameness on one or both rear legs, but you may not notice any signs of discomfort in a dog with hip dysplasia. As the dog ages, arthritis can develop. Dogs with hip dysplasia should not be bred. If you’re buying a puppy, ask the breeder for proof that the parents have been tested for hip dysplasia and are free of problems. Heart Murmurs: Heart murmurs are caused by a disturbance in the blood flow through the chambers of the heart. They’re an indicator that there may be a disease or condition of the heart that will need to be monitored and treated. Sources: https://en.wikipedia.org/wiki/Affenpinscher https://dogtime.com/dog-breeds/affenpinscher#/slide/1 https://www.yourpurebredpuppy.com/reviews/affenpinschers.html Photo credit: https://www.thesprucepets.com/breed-profile-affenpinscher-1117931
Feline Blood-Types
[vc_row][vc_column][vc_column_text] Feline Blood-Types Andy Pachikerl, Ph.D Introduction Like humans, cats have blood grouping. However, cats do not have the blood-type O positive. The blood type classification of cats, however, is currently based on the AB system, but like dogs, there are other antigens besides the AB system , such as the Mik blood type. The blood type of cats is composed of mainly A, B, and AB. Type A is the most common, type B is rarer, and type AB is rarest. About 95% of domestic cats are type A blood, and some varieties such as exotic short-haired cats, British short-haired cats, Persian cats, and Scottish folds have a higher percentage of type B blood. As mentioned, the blood-type of cats is mainly A, B, or AB. Peculiarly for AB type, other blood types have innate antibodies. Unlike dogs, cats have antibodies against “non-self” or foreign erythrocytes that can cause lethal immuno -reaction. Therefore, cats cannot obtain a “wrong” blood of different blood types. Before any blood transfusion clinically, cat blood typing is extremely important. Incompatibility of blood type can lead to fatal acute hemolysis reaction, particularly, the blood of a type A cat was given to a type B cat. The anti-type B antibodies found in type A cats have weaker affinity towards each other, causing a mild immune response. However, type B cats have a strong affiliated anti-type A antibody, which can cause a strong immune response. Once type B cat transfuses A-type blood, the red blood cells are rapidly destroyed,resulting in intravascular hemolysis. As little as 1 ml of type A cat blood, it is enough to cause a serious immune reaction in type B cat and then causes absolute lethality. Keep in mind that blood typing is not only extremely vital prior a blood transfusion, but also for cat breeding! Neonatal isoerythrolysis (NI) occurs when a mommy cat with type B blood gives birth to kittens with type A or AB blood and breast-feed them with a high chance of having antigens of type A blood antibodies in the milk, which can cause a severe hemolysis reaction in the kittens. There are no obvious clinical signs to severe hemolytic anemia, but only subtle symptoms such as hemoglobinuria and jaundice. Therefore, we must pay attention to the blood type of the parent before breeding. Despite the best of efforts to prevent them, transfusion reactions may still happen. Depending on the severity, therapy can include glucocorticoids, epinephrine, IV fluids, and discontinuing the transfusion. Fever is usually mild, requiring no treatment. Furosemide should be administered if volume overload occurs. The blood product can be warmed to no more than 37 ° C if hypothermia occurs. Crossmatching blood is the best means of preventing immune-mediated transfusion reactions even if the blood type is known for both cats. It is also imperative blood be collected and administered as aseptically as possible and cats receiving blood products are monitored carefully. The distribution of feline blood types varies by geographic region and breed (Table 1) 1-2. Type-A is the most common type among most cats. There is, however, geographic variation in the prevalence of type-B domestic shorthaired cats. Over 10% of the domestic shorthair cats in Australia, Italy, France and India are type- B. Breed distribution does not vary as much by location because of the international exchange of breeding cats. Over 30% of British Shorthair cats, Cornish and Devon Rex cats, and Turkish Angora or Vans have type-B blood. In contrast, Siamese and related breeds are almost exclusively type-A. Ragdoll cats appear to be unique regarding blood types. Approximately 3.2% of Ragdoll cats are discordant for blood group when genotyping is compared to serology, necessitating further investigation in this breed. Table 1: Selected Blood Type A and B Frequencies in Cats (ignoring AB blood types) The AB blood type is very rare while the frequency of the MiK blood type is unknown. The presence of red blood cell antigens in addition to the AB group may explain why transfusion compatibility is not guaranteed by blood typing; crossmatching is recommended prior to any transfusion 3. Breeding queens, along with blood donors and, if possible, blood recipients should be blood typed. Feline blood-typing methods There are various methods are that can be used to determine blood type, both in a laboratory and veterinarian clinic. Usually in a diagnostic laboratory, they would use various serological methods by adding reagents to samples of blood and observe for any agglutination reactions marking a positive result. In addition, genetic testing is now available to identify blood types A and B using buccal swabs, although it cannot distinguish between A and AB blood groups. In veterinarian clinics, testing may be performed using a card typing system (BIOGUARD® Feline blood -typing kit, New Taipei City, Taiwan and Rapid Vet-H®, Flemington, NJ). If the card-typing system is used, type-AB and type-B results should be confirmed by a referral laboratory as some cross-reactions have been known to occur. Recently,there was an introduction to an alternative novel method for blood typing ie using the gel column agglutination test (DiaMed-Vet® feline typing gel, DiaMed, Switzerland). This test is easier to interpret than the card method, although it requires a specially designed centrifuge that may be cost-prohibitive in some settings. An evaluation of various blood typing kits and methods revealed that accuracy of blood type must be high and working hand in hand with time efficiency. A complete comparison of kits and methods for blood typing is as follow.An evaluation of various blood typing kits and methods revealed that accuracy of blood type must be high and working hand in hand with time efficiency. A complete comparison of kits and methods for blood typing is as follow.An evaluation of various blood typing kits and methods revealed that accuracy of blood type must be high and working hand in hand with time efficiency. A complete comparison of kits and methods for blood typing is